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Sex Differences

Which aspects (gender, sexual, social, or other) prevail in explaining the observed differences in Covid-19 outcomes between men and women?

There have been marked differences in COVID-19's presentation between men and women, from symptom severity to mortality rates. Based on a CDC report in July 2020, more men have died of COVID-19 in 41 out of 47 countries. This trend is prominent enough to draw concern from the scientific community, and has been identified as a key research area for Circular Health.

COVID-19 Retrospective Cohort Study

This research group aims to identify the clinical and environmental factors that underlie the differences between male and female patients through the collection of data in member in partner hospitals. Key factors will include:

  • Age
  • Ethnicity
  • Employment Status
  • Smoking Status
  • Comorbidities
  • Treatment, Care Outcomes, and more

Gender by Default

While the differences in COVID outcomes between men and women are well documented, many clinical trials on COVID vaccines and other related studies do not report gender/sex data. Circular Health calls for a Gender by Default standard for reporting information such as subject sex and/or gender to determine COVID and other infectious disease's different impact on these groups.

Read more:


Explore Circular Health

  • Overarching Themes
    • Gender by Default
    • Citizen Empowerment
    • Interdisciplinarity

Main SDGs

Sex Differences in News/Research

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